The March issue of Nature Rev. Neuroscience includes an interesting article about an herbal remedy, ibogaine, which appears to upregulate glial-derived neurotrophic factor (GDNF) in the VTA (ventral tegmental area, which seems to play a key role in reward learning). Apparently, an increase in GDNF activity makes alcohol (and presumably other VTA-involved compounds, like opiates) less addictive.
This entry was posted on Monday, March 14th, 2005 at 11:58 pm by Neville Sanjana and is filed under Medicine. You can follow any responses to this entry through the RSS 2.0 feed. You can skip to the end and leave a response. Pinging is currently not allowed.
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March 7th, 2006 at 4:15 pm
thought ibogaine just gave you a massive psychadelic kick which might or might not take you out of an addiction cycle, good to hear it’s actaully got a real mechanism of action