Dopamine D_3 agonist leads to compulsive gambling, hedonism
11 patients taking dopamine agonists for Parkinson’s developed compulsive gambling, sometimes accompanied with hypersexuality. A retrospective study of one clinic found that 1.5% of 529 patients taking pramipexole developed compulsive gambling. Pramipexole is a D_3 agonist. D_3 receptors are located in the limbic system.
The article is short and the case studies are interesting. Interestingly, many of the patients profiled recognized a change in their behavior and thought it was abnormal for them to be obsessed with gambling, and told their neurologist.
M. Leann Dodd, MD; Kevin J. Klos, MD; James H. Bower, MD; Yonas E. Geda, MD; Keith A. Josephs, MST, MD; J. Eric Ahlskog, PhD, MD. Pathological Gambling Caused by Drugs Used to Treat Parkinson Disease. Arch Neurol. 2005;62
April 19th, 2006 at 8:46 pm
it hapens with me.
under pramipexole I had the side efect GAMBLING. i WAS 55 AND NEVER PLAYED
WITH MONEY, UNTIL PRAMIPEXOLE. I LOST MUCH MONEY, FRIENDS, CLIENTES, HEALTH AND DIGNITY.
I LOOKING FOR NEW LIFE. ONLY GOD CAN SAVE ME.
WHAT DO YOU CAN TELL ABOUT CLASS ACTION? THE COURTS DAID ANYTHING?
DO YOU KNOW OTHER CASE IN BRAZIL?