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Bistable current photoswitches in neurons

Posted by Neville Sanjana at 1:01 AM EST

Bi-stable neural state switches : Article : Nature Neuroscience

Another channelrhodopsin breakthrough from Deisseroth’s lab. This time light is not required to keep the channel open. Light merely triggers opening and closing behavior. Blue-shifted light opens channels and red-shifted light closes them. This looks like another potentially powerful neurotechnology for interrogating circuits and systems.

Relevant fig:

This entry was posted on Monday, January 12th, 2009 at 1:01 am by Neville Sanjana and is filed under Culture (in vitro), Genetics and molecular, Ion channels, Neuroengineering. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

One Response to “Bistable current photoswitches in neurons”

A Goldstein Says:
March 11th, 2010 at 4:54 pm
Exciting! We’re giving a Wiley Prize to the scientists who discovered channelrhodopsins, so it’s awesome to see these being applied.

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