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	<title>neurodudes &#187; Data analysis</title>
	<atom:link href="http://neurodudes.com/category/computational-neuroscience/data-analysis/feed/" rel="self" type="application/rss+xml" />
	<link>http://neurodudes.com</link>
	<description>at the intersection of neuroscience and AI.</description>
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		<title>ConnectomeViewer &#8211; Multi-Modal Multi-Level Network and Neuroimaging Visualization and Analysis</title>
		<link>http://neurodudes.com/2010/05/24/connectomeviewer-multi-modal-multi-level-network-and-neuroimaging-visualization-and-analysis/</link>
		<comments>http://neurodudes.com/2010/05/24/connectomeviewer-multi-modal-multi-level-network-and-neuroimaging-visualization-and-analysis/#comments</comments>
		<pubDate>Tue, 25 May 2010 02:29:22 +0000</pubDate>
		<dc:creator>Bayle Shanks</dc:creator>
				<category><![CDATA[Data analysis]]></category>
		<category><![CDATA[Software and online tools]]></category>
		<category><![CDATA[connectome]]></category>

		<guid isPermaLink="false">http://neurodudes.com/?p=1749</guid>
		<description><![CDATA[Two neat tools concerned with the &#8220;connectome&#8221; (i.e. the pattern of connections in the nervous system): Semantic wiki: http://www.connectome.ch/wiki/Main_Page Desktop viewer: http://connectomeviewer.org/viewer &#8220;Multi-Modal Multi-Level Network and Neuroimaging Visualization and Analysis&#8221; (screencasts)]]></description>
			<content:encoded><![CDATA[<p>Two neat tools concerned with the &#8220;connectome&#8221; (i.e. the pattern of connections in the nervous system):</p>
<p>Semantic wiki:<br />
<a href="http://www.connectome.ch/wiki/Main_Page">http://www.connectome.ch/wiki/Main_Page</a></p>
<p>Desktop viewer:<br />
<a href="http://connectomeviewer.org/viewer">http://connectomeviewer.org/viewer</a> &#8220;Multi-Modal Multi-Level Network and Neuroimaging Visualization and Analysis&#8221; <a href="http://www.connectomeviewer.org/viewer/screencasts">(screencasts)</a></p>
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		<slash:comments>2</slash:comments>
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		<title>Over time, distribution of shot lengths in movies has moved closer to pink noise</title>
		<link>http://neurodudes.com/2010/03/02/over-time-distribution-of-shot-lengths-in-movies-has-moved-closer-to-pink-noise/</link>
		<comments>http://neurodudes.com/2010/03/02/over-time-distribution-of-shot-lengths-in-movies-has-moved-closer-to-pink-noise/#comments</comments>
		<pubDate>Tue, 02 Mar 2010 06:12:47 +0000</pubDate>
		<dc:creator>Bayle Shanks</dc:creator>
				<category><![CDATA[Cognitive science]]></category>
		<category><![CDATA[Data analysis]]></category>

		<guid isPermaLink="false">http://neurodudes.com/?p=870</guid>
		<description><![CDATA[The statistics of shot durations in 150 films from 1935 to 2005 were analyzed. From about 1970 to the present, the power spectrum of shot durations in individual films has tended to become more like pink noise (power ~= 1/f). Also, autocorrelation shows that the lengths of nearby shots has become more and more correlated. [...]]]></description>
			<content:encoded><![CDATA[<p>The statistics of shot durations in 150 films from 1935 to 2005 were analyzed. From about 1970 to the present, the power spectrum of shot durations in individual films has tended to become more like pink noise (power ~= 1/f). Also, autocorrelation shows that the lengths of nearby shots has become more and more correlated.</p>
<p><span id="more-870"></span></p>
<p>The authors, Cutting, DeLong, and Nothelfer, speculate that the pink noise bit is being driven by some process that is related to attention, since there are some other results (which they cite) showing the relevance of pink noise to attention.</p>
<p>However, IMDB ratings were not positively correlated with the pink-noise-ness of the movie (partial correlation with release date factored out).</p>
<p>Incidentally, <a href="http://continuityboy.blogspot.com/2010/02/new-scientist-and-1f-structure-in-film.html">this guy</a> did his PhD thesis on cognitive science explanations for film editing techniques.</p>
<p>James E. Cutting, Jordan E. DeLong, and Christine E. Nothelfer. Attention and the Evolution of Hollywood Film. Psychological Science February 2010 , first published on February 5, 2010 <a href="http://pss.sagepub.com/content/early/2010/02/04/0956797610361679" alt="(note: the doi is broken so we used a different URL)">doi:10.1177/0956797610361679</a>.</p>
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		<item>
		<title>STAToolkit</title>
		<link>http://neurodudes.com/2010/02/18/statoolkit/</link>
		<comments>http://neurodudes.com/2010/02/18/statoolkit/#comments</comments>
		<pubDate>Fri, 19 Feb 2010 00:48:04 +0000</pubDate>
		<dc:creator>Bayle Shanks</dc:creator>
				<category><![CDATA[Data analysis]]></category>
		<category><![CDATA[Methods and techniques]]></category>

		<guid isPermaLink="false">http://neurodudes.com/?p=862</guid>
		<description><![CDATA[http://neuroanalysis.org/ Octave/MATLAB toolkit for analysis of spike train data. Open source. Information theory-y.]]></description>
			<content:encoded><![CDATA[<p><a href="http://neuroanalysis.org/">http://neuroanalysis.org/</a></p>
<p>Octave/MATLAB toolkit for analysis of spike train data. Open source. Information theory-y.</p>
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		<slash:comments>1</slash:comments>
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		<title>Dead salmon in fMRI machine shows signs of thought (not really)</title>
		<link>http://neurodudes.com/2009/09/21/dead-salmon-in-fmri-machine-shows-signs-of-thought-not-really/</link>
		<comments>http://neurodudes.com/2009/09/21/dead-salmon-in-fmri-machine-shows-signs-of-thought-not-really/#comments</comments>
		<pubDate>Mon, 21 Sep 2009 19:46:50 +0000</pubDate>
		<dc:creator>Bayle Shanks</dc:creator>
				<category><![CDATA[Data analysis]]></category>

		<guid isPermaLink="false">http://neurodudes.com/?p=792</guid>
		<description><![CDATA[This poster, by Bennett, Baird, Miller, and Wolford, provides a memorable reminder that you have to do a statistical correction for multiple comparisons when you datamine a large number of things for correlation. &#8220;The task administered to the salmon involved completing an open-ended mentalizing task. The salmon was shown a series of photographs depicting human [...]]]></description>
			<content:encoded><![CDATA[<p>This poster, by Bennett, Baird, Miller, and Wolford, provides a memorable reminder that you have to do a statistical correction for multiple comparisons when you datamine a large number of things for correlation.</p>
<p>&#8220;The task administered to the salmon involved completing an open-ended mentalizing task. The salmon was shown a series of photographs depicting human individuals in social situations with a specified emotional valence. The salmon was asked to determine what emotion the individual in the photo must have been experiencing.&#8221;</p>
<p><span id="more-792"></span></p>
<p>Voxels in the data were searched to find voxels which show a statistically significant correlation with the experimental condition. 16 such voxels were found (without doing any correction). As the poster says, &#8220;Across the 130,000 voxels in a typical fMRI volume the probability of a false positive is almost certain&#8221;. The poster recommends correcting with either &#8220;overall false discovery rate (FDR) &#8230; based on a method defined by Benjamini and Hochberg (1995)&#8221; or &#8220;overall familywise error rate (FWER) &#8230;. using algorithms originally devised by Friston et al. (1994)&#8221; (with either correction, no voxels were found).<br />
<a href=" http://prefrontal.org/files/posters/Bennett-Salmon-2009.pdf"></p>
<p>http://prefrontal.org/files/posters/Bennett-Salmon-2009.pdf</a></p>
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		<item>
		<title>Frontiers in Neuroscience Journal</title>
		<link>http://neurodudes.com/2009/08/16/frontiers-in-neuroscience-journal/</link>
		<comments>http://neurodudes.com/2009/08/16/frontiers-in-neuroscience-journal/#comments</comments>
		<pubDate>Sun, 16 Aug 2009 21:02:16 +0000</pubDate>
		<dc:creator>Stephen Larson</dc:creator>
				<category><![CDATA[Brain-machine interfaces]]></category>
		<category><![CDATA[Cog/neuro science careers]]></category>
		<category><![CDATA[Computation within single neurons]]></category>
		<category><![CDATA[Computational neuroscience]]></category>
		<category><![CDATA[Conferences]]></category>
		<category><![CDATA[Consumer neurotechnology]]></category>
		<category><![CDATA[Data analysis]]></category>
		<category><![CDATA[Education]]></category>
		<category><![CDATA[Evolution]]></category>
		<category><![CDATA[Genetics and molecular]]></category>
		<category><![CDATA[Interdisciplinary concepts]]></category>
		<category><![CDATA[Internet and blogs]]></category>
		<category><![CDATA[Ion channels]]></category>
		<category><![CDATA[Jobs]]></category>
		<category><![CDATA[Medicine and other intervention/augmentation]]></category>
		<category><![CDATA[Memory and learning]]></category>
		<category><![CDATA[Methods and techniques]]></category>
		<category><![CDATA[Networks]]></category>
		<category><![CDATA[Neural development]]></category>
		<category><![CDATA[Neural network models]]></category>
		<category><![CDATA[Neural regeneration/neurogenesis]]></category>
		<category><![CDATA[Neuroanatomy]]></category>
		<category><![CDATA[Neuroengineering]]></category>
		<category><![CDATA[Neuronal arbors/neurites]]></category>
		<category><![CDATA[Neuropharmacology]]></category>
		<category><![CDATA[News, conferences, books, jobs, etc]]></category>
		<category><![CDATA[Robotics]]></category>
		<category><![CDATA[Systems biology]]></category>
		<category><![CDATA[Theory/Philosophy]]></category>

		<guid isPermaLink="false">http://neurodudes.com/?p=767</guid>
		<description><![CDATA[The journal, Frontiers in Neuroscience, edited by Idan Segev, has made it Volume 3, issue 1.  Launching last year at the Society for Neuroscience conference, its probably the newest Neuroscience-related journal. I&#8217;m a fan of it because it is an open-access journal featuring a &#8220;tiered system&#8221; and more.  From their website: The Frontiers Journal Series [...]]]></description>
			<content:encoded><![CDATA[<p>The journal, <a href="http://www.frontiersin.org/neuroscience/">Frontiers in Neuroscience</a>, edited by Idan Segev, has made it Volume 3, issue 1.  Launching last year at the Society for Neuroscience conference, its probably the newest Neuroscience-related journal.</p>
<p>I&#8217;m a fan of it because it is an open-access journal featuring a &#8220;tiered system&#8221; and more.  <a href="http://www.frontiersin.org/aboutfrontiers/">From their website</a>:</p>
<blockquote><p>The Frontiers Journal Series is not just another journal. It is a new approach to scientific publishing. As service to scientists, it is driven by researchers for researchers but it also serves the interests of the general public. <strong>Frontiers </strong>disseminates research in a <a style="text-decoration: none;" href="http://www.frontiersin.org/publishingprocess/"><span style="color: #000000;">tiered system</span></a> that begins with original articles submitted to Specialty Journals. It <a style="text-decoration: none;" href="http://www.frontiersin.org/evaluationsystem/"><span style="color: #000000;">evaluates</span></a> research truly democratically and objectively based on the reading activity of the scientific communities and the public. And it drives the most outstanding and relevant research up to the next tier journals, <a style="font-size: 12px; list-style-type: none; list-style-position: initial; list-style-image: initial; text-decoration: none; padding: 0px;" href="http://www.frontiersin.org/"><span style="color: #000000;">the Field Journals</span></a><span style="color: #000000;">.</span></p></blockquote>
<p><span id="more-767"></span></p>
<p>I&#8217;m a big fan of the variety of specialty journals they have:</p>
<ul>
<li>Aging Neuroscience</li>
<li>Behavioral Neuroscience</li>
<li>Cellular Neuroscience</li>
<li>Computational Neuroscience</li>
<li>Enteric Neuroscience</li>
<li>Evolutionary Neuroscience</li>
<li>Human Neuroscience</li>
<li>Integrative Neuroscience</li>
<li>Molecular Neuroscience</li>
<li>Neural Circuits</li>
<li>Neuroanatomy</li>
<li>Neuroenergetics</li>
<li>Neuroengineering</li>
<li>Neurogenesis</li>
<li>Neurogenomics</li>
<li>Neuroinformatics</li>
<li>Neuromethods</li>
<li>Neuropharamacology</li>
<li>Neuroprosthetics</li>
<li>Neurorobotics</li>
<li>Synaptic Neuroscience</li>
<li>Systems Neuroscience</li>
</ul>
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		<item>
		<title>Transcriptomics of the fetal human brain</title>
		<link>http://neurodudes.com/2009/07/02/transcriptomics-of-the-fetal-human-brain/</link>
		<comments>http://neurodudes.com/2009/07/02/transcriptomics-of-the-fetal-human-brain/#comments</comments>
		<pubDate>Thu, 02 Jul 2009 04:59:16 +0000</pubDate>
		<dc:creator>Neville Sanjana</dc:creator>
				<category><![CDATA[Cortex]]></category>
		<category><![CDATA[Data analysis]]></category>
		<category><![CDATA[Genetics and molecular]]></category>
		<category><![CDATA[Methods and techniques]]></category>

		<guid isPermaLink="false">http://neurodudes.com/?p=685</guid>
		<description><![CDATA[A cutting-edge application of the Affy total human exome GeneChip (4X coverage per exon, 40X coverage per gene): Functional and Evolutionary Insights into Human Brain Development through Global Transcriptome Analysis. From the News and Views, I was intrigued to learn that previous transcriptome analyses of adult human brains found very little difference in gene expression [...]]]></description>
			<content:encoded><![CDATA[<p>A cutting-edge application of the <a href="http://www.affymetrix.com/products_services/arrays/specific/exon.affx">Affy total human exome GeneChip</a> (4X coverage per exon, 40X coverage per gene): <a href="http://dx.doi.org/10.1016/j.neuron.2009.03.027">Functional and Evolutionary Insights into Human Brain Development through Global Transcriptome Analysis</a>.</p>
<p>From the <a href="http://dx.doi.org/10.1016/j.neuron.2009.05.006">News and Views</a>, I was intrigued to learn that previous <a href="http://en.wikipedia.org/wiki/Transcriptomics">transcriptome</a> analyses of adult human brains found very little difference in gene expression between brain areas:</p>
<blockquote><p>[...] this suggests that it is the gene expression during development that largely determines higher brain functions by specifying the complexity of neural connections. Numerically, the most important genes relating to cognitive differences between species may be genes that specify how the machinery is put together. In support of this hypothesis, many of the identified differentially expressed genes in this study are related to processes involved in connection formation, such as axonal guidance and cell adhesion.</p></blockquote>
<p>An impressive 76% of all human genes are expressed in the developing fetal brain. Of those, 33% are differentially expressed over brain regions (13 regions were examined) and 28% are alternatively spliced. The differentially expressed genes are also ones that seem to have evolved the most recently. Even in these early (midgestation) stages, left-right asymmetry was seen, such as the localization of the language-associated <a href="http://en.wikipedia.org/wiki/FOXP2">FOXP2</a> genes to Broca&#8217;s area.</p>
<p>Of interest to computational folks, they find that gene expression follows <a href="http://en.wikipedia.org/wiki/Zipf%27s_law">power-law scaling</a> (as many other naturally occurring <a href="http://www.nature.com/nature/journal/v393/n6684/abs/393440a0.html">&#8220;small-worlds&#8221; networks</a> do) with certain hub genes connected to many others and certain spoke genes with relatively few connections. Unsupervised hierarchical clustering is used in this analysis.</p>
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		<item>
		<title>Social neuroscience fMRI: Specious correlations?</title>
		<link>http://neurodudes.com/2009/01/17/social-neuroscience-fmri-specious-correlations/</link>
		<comments>http://neurodudes.com/2009/01/17/social-neuroscience-fmri-specious-correlations/#comments</comments>
		<pubDate>Sat, 17 Jan 2009 20:02:11 +0000</pubDate>
		<dc:creator>Neville Sanjana</dc:creator>
				<category><![CDATA[Cognitive science]]></category>
		<category><![CDATA[Data analysis]]></category>
		<category><![CDATA[Discussion]]></category>
		<category><![CDATA[Imaging]]></category>
		<category><![CDATA[Neuroethology]]></category>

		<guid isPermaLink="false">http://neurodudes.com/?p=520</guid>
		<description><![CDATA[Nature is reporting on potential flaw in multiple imaging (fMRI) studies of social neuroscience. Ed Vul (a graduate student in my dept) and colleagues have a paper in press that says that many of the high correlations between brain regions and social behavior are implausible, given the inherent variability/noise in fMRI. Furthermore, based on a [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://www.nature.com/news/2009/090113/full/457245a.html">Nature is reporting on potential flaw</a> in multiple imaging (<a href="http://en.wikipedia.org/wiki/Functional_magnetic_resonance_imaging">fMRI</a>) studies of social neuroscience. <a href="http://www.edvul.com/voodoocorr.php">Ed Vul</a> (a graduate student in <a href="http://web.mit.edu/bcs/">my dept</a>) and colleagues have <a href="http://www.pashler.com/Articles/Vul_etal_2008inpress.pdf">a paper in press</a> that says that many of the high correlations between brain regions and social behavior are implausible, given the inherent variability/noise in fMRI. Furthermore, based on a survey of methods from individual investigators, they created a list of papers that commit, in their view, a statistical mistake (<a href="http://en.wikipedia.org/wiki/Non-Independence_Error">non-independence</a>). Naturally, the authors named in the paper aren&#8217;t happy and, according to the Nature article, several rebuttals are in the works. At the very least, to my non-expert eyes, this seems like an important discussion to have about data analysis and methodology.</p>
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